WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 527605
Description: Valibose An α-glucosidase inhibitor potentially for the treatment of diabetes. Valibose significantly decreased postprandial and fasting blood glucose, urine glucose, and reduced the levels of serum fructosamine. Valibose also decreased plasma triglyceride and cholesterol levels. Valibose ameliorated metabolic disturbance of glucose and lipids. In addition, valibose markedly reduced level of serum NAG and BUN, and decreased the weight index of kidney.
MedKoo Cat#: 527605
Chemical Formula: C10H21NO6
Exact Mass: 251.1369
Molecular Weight: 251.279
Elemental Analysis: C, 47.80; H, 8.42; N, 5.57; O, 38.20
IUPAC/Chemical Name: (1R,2S,3S,4S,6R)-4-((1,3-dihydroxypropan-2-yl)amino)-6-(hydroxymethyl)cyclohexane-1,2,3-triol
InChi Key: LWJUMCBIHCZWBT-JTBFQXKRSA-N
InChi Code: InChI=1S/C10H21NO6/c12-2-5-1-7(11-6(3-13)4-14)9(16)10(17)8(5)15/h5-17H,1-4H2/t5-,7+,8-,9+,10+/m1/s1
SMILES Code: O[C@H]1[C@@H](NC(CO)CO)C[C@H](CO)[C@@H](O)[C@@H]1O
1: Liu Q, Liu SN, Sun SJ, Shen ZF. [Valibose, an alpha-glucosidase inhibitor, ameliorates the metabolic disorder of glucose and lipids and the nephropathy in streptozotocin-induced diabetic rats]. Yao Xue Xue Bao. 2013 Aug;48(8):1227-32. Chinese. PubMed PMID: 24187828.
2: Zhong S, Zhong D, Chen X. Improved and simplified liquid chromatography/electrospray ionization mass spectrometry method for the analysis of underivatized glucosamine in human plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Jul 1;854(1-2):291-8. PubMed PMID: 17544344.
3: Dai XM, An N, Wu JM, Li HY, Zhang QM. Development and validation of HPLC-UV-MS method for the control of four anti-diabetic drugs in suspected counterfeit products. Yao Xue Xue Bao. 2010 Mar;45(3):347-52. PubMed PMID: 21348424.