BC11-38

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 531568

CAS#: 686770-80-9

Description: BC 11-38 is a selective inhibitor of PDE11 with an IC50 value of 0.28 μM.


Price and Availability

Size
Price

Size
Price

Size
Price

BC11-38 , is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

img

Theoretical Analysis

MedKoo Cat#: 531568
Name: BC11-38
CAS#: 686770-80-9
Chemical Formula: C15H16N2OS2
Exact Mass: 304.0704
Molecular Weight: 304.43
Elemental Analysis: C, 59.18; H, 5.30; N, 9.20; O, 5.26; S, 21.06


Synonym: BC11-38; BC 11-38; BC-11-38.

IUPAC/Chemical Name: 3-phenyl-2-(propylsulfanyl)-3H,4H,6H,7H-thieno[3,2-d]pyrimidin-4-one

InChi Key: YHNDCCKFNWDQGW-UHFFFAOYSA-N

InChi Code: InChI=1S/C15H16N2OS2/c1-2-9-20-15-16-12-8-10-19-13(12)14(18)17(15)11-6-4-3-5-7-11/h3-7H,2,8-10H2,1H3

SMILES Code: O=C1C2=C(CCS2)N=C(SCCC)N1C3=CC=CC=C3


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Qiu YL, Gong JY, Feng JY, Wang RX, Han J, Liu T, Lu Y, Li LT, Zhang MH, Sheps JA, Wang NL, Yan YY, Li JQ, Chen L, Borchers CH, Sipos B, Knisely AS, Ling V, Xing QH, Wang JS. Defects in MYO5B are associated with a spectrum of previously undiagnosed low γ-glutamyltransferase cholestasis. Hepatology. 2016 Dec 27. doi: 10.1002/hep.29020. [Epub ahead of print] PubMed PMID: 28027573.

2: Ronsley R, Scott D, Warburton WP, Hamdi RD, Louie DC, Davidson J, Panagiotopoulos C. A population-based study of antipsychotic prescription trends in children and adolescents in British Columbia, from 1996 to 2011. Can J Psychiatry. 2013 Jun;58(6):361-9. PubMed PMID: 23768264.

3: Goldberg E, Paul M, Talker O, Samra Z, Raskin M, Hazzan R, Leibovici L, Bishara J. Co-trimoxazole versus vancomycin for the treatment of methicillin-resistant Staphylococcus aureus bacteraemia: a retrospective cohort study. J Antimicrob Chemother. 2010 Aug;65(8):1779-83. doi: 10.1093/jac/dkq179. PubMed PMID: 20507860.