BAY-73-1449

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 531564

CAS#: 693790-96-4

Description: BAY-73-1449 is a prostacyclin receptor antagonist.


Price and Availability

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BAY-73-1449 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 531564
Name: BAY-73-1449
CAS#: 693790-96-4
Chemical Formula: C26H23N3O3
Exact Mass: 425.1739
Molecular Weight: 425.49
Elemental Analysis: C, 73.39; H, 5.45; N, 9.88; O, 11.28


Synonym: BAY-73-1449; BAY73-1449; BAY 73-1449

IUPAC/Chemical Name: (2S)-3-phenyl-2-[[6-[4-(phenylmethoxy)phenyl]pyrimidin-4-yl]amino]propanoic acid

InChi Key: RRYFPNITZGCUPZ-DEOSSOPVSA-N

InChi Code: InChI=1S/C26H23N3O3/c30-26(31)24(15-19-7-3-1-4-8-19)29-25-16-23(27-18-28-25)21-11-13-22(14-12-21)32-17-20-9-5-2-6-10-20/h1-14,16,18,24H,15,17H2,(H,30,31)(H,27,28,29)/t24-/m0/s1

SMILES Code: O=C(O)[C@@H](NC1=NC=NC(C2=CC=C(OCC3=CC=CC=C3)C=C2)=C1)CC4=CC=CC=C4


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Bexis S, McCormick PA, Docherty JR. Vascular actions of the prostacyclin receptor antagonist BAY 73-1449 in the portal hypertensive rat. Eur J Pharmacol. 2008 Aug 20;590(1-3):322-6. doi: 10.1016/j.ejphar.2008.06.006. PubMed PMID: 18603238.