Hexasodium phytate

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MedKoo CAT#: 529817

CAS#: 34367-89-0 (Hexasodium phytate)

Description: Hexasodium phytate is a hydroxyapatite formation inhibitor. It could potentially be used for the treatment of vascular calcification and calciphylaxis.

Chemical Structure

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Hexasodium phytate
CAS# 34367-89-0 (Hexasodium phytate)
Instruction

Theoretical Analysis

MedKoo Cat#: 529817
Name: Hexasodium phytate
CAS#: 34367-89-0 (Hexasodium phytate)
Chemical Formula: C6H12Na6O24P6
Exact Mass: 791.75
Molecular Weight: 791.919
Elemental Analysis: C, 9.10; H, 1.53; Na, 17.42; O, 48.49; P, 23.47

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Related CAS #: 34367-89-0 (Hexasodium phytate)   83-86-3 (Phyliance)  

Synonym: Hexasodium phytate; Hexasodium-phytate; SNF-472; SNF472; SNF 472; Fytate d'hexasodium; Fitato de hexasodio;

IUPAC/Chemical Name: sodium cyclohexane-1,2,3,4,5,6-hexayl hexakis(hydrogen phosphate)

InChi Key: DHZIAGCFFSRULK-UHFFFAOYSA-H

InChi Code: InChI=1S/C6H18O24P6.6Na/c7-31(8,9)25-1-2(26-32(10,11)12)4(28-34(16,17)18)6(30-36(22,23)24)5(29-35(19,20)21)3(1)27-33(13,14)15;;;;;;/h1-6H,(H2,7,8,9)(H2,10,11,12)(H2,13,14,15)(H2,16,17,18)(H2,19,20,21)(H2,22,23,24);;;;;;/q;6*+1/p-6

SMILES Code: O=P(OC1C(OP([O-])(O)=O)C(OP([O-])(O)=O)C(OP([O-])(O)=O)C(OP([O-])(O)=O)C1OP([O-])(O)=O)([O-])O.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 791.92 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Zabirnyk A, Ferrer MD, Bogdanova M, Pérez MM, Salcedo C, Kaljusto ML, Kvitting JP, Stensløkken KO, Perelló J, Vaage J. SNF472, a novel anti- crystallization agent, inhibits induced calcification in an in vitro model of human aortic valve calcification. Vascul Pharmacol. 2019 Nov-Dec;122-123:106583. doi: 10.1016/j.vph.2019.106583. Epub 2019 Aug 19. PMID: 31437530.

2: Creeth JE, Parkinson CR, Burnett GR, Sanyal S, Lippert F, Zero DT, Hara AT. Effects of a sodium fluoride- and phytate-containing dentifrice on remineralisation of enamel erosive lesions-an in situ randomised clinical study. Clin Oral Investig. 2018 Sep;22(7):2543-2552. doi: 10.1007/s00784-018-2351-z. Epub 2018 Feb 8. PMID: 29423713; PMCID: PMC6097037.

3: Milleman KR, Creeth JE, Burnett GR, Milleman JL. A randomized clinical trial to evaluate the stain removal efficacy of a sodium phytate dentifrice formulation. J Esthet Restor Dent. 2018 Mar;30(2):E45-E51. doi: 10.1111/jerd.12355. Epub 2018 Feb 7. PMID: 29411532; PMCID: PMC5969293.

4: Perelló J, Gómez M, Ferrer MD, Rodríguez NY, Salcedo C, Buades JM, Pérez MM, Torregrosa JV, Martín E, Maduell F. SNF472, a novel inhibitor of vascular calcification, could be administered during hemodialysis to attain potentially therapeutic phytate levels. J Nephrol. 2018 Apr;31(2):287-296. doi: 10.1007/s40620-018-0471-9. Epub 2018 Jan 19. PMID: 29350348; PMCID: PMC5829128.