YK11
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 530400

CAS#: 1370003-76-1

Description: YK-11 is a synthetic, steroidal selective androgen receptor modulator (SARM). It is a gene-selective partial agonist of the androgen receptor (AR) and does not induce the physical interaction between the NTD/AF1 and LBD/AF2 (known as the N/C interaction), which is required for full transactivation of the AR. The drug has anabolic activity in vitro in C2C12 myoblasts and shows greater potency than dihydrotestosterone (DHT) in this regard.


Price and Availability

Size
Price

500mg
USD 250
5g
USD 1450
Size
Price

1g
USD 450
10g
USD 2250
Size
Price

2g
USD 850
50g
USD 4950

YK-11, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received. Delivery time: overnight (USA/Canada); 3-5 days (worldwide).


Chemical Structure

img

Theoretical Analysis

MedKoo Cat#: 530400
Name: YK11
CAS#: 1370003-76-1
Chemical Formula: C25H34O6
Exact Mass: 430.2355
Molecular Weight: 430.541
Elemental Analysis: C, 69.74; H, 7.96; O, 22.30


Synonym: YK-11; YK 11; YK11.

IUPAC/Chemical Name: methyl (E)-2-((8R,9S,10R,13S,14S,17R)-2'-methoxy-2',13-dimethyl-3-oxo-1,2,3,6,7,8,9,10,11,12,13,14,15,16-tetradecahydrospiro[cyclopenta[a]phenanthrene-17,4'-[1,3]dioxolan]-5'-ylidene)acetate

InChi Key: KCQHQCDHFVGNMK-DEIKBOPOSA-N

InChi Code: InChI=1S/C25H34O6/c1-23-11-9-18-17-8-6-16(26)13-15(17)5-7-19(18)20(23)10-12-25(23)21(14-22(27)28-3)30-24(2,29-4)31-25/h13-14,17-20H,5-12H2,1-4H3/b21-14+/t17-,18+,19+,20-,23-,24?,25-/m0/s1

SMILES Code: C[C@@]12[C@](/C3=C\C(OC)=O)(OC(OC)(O3)C)CC[C@@]1([H])[C@]4([H])CCC5=CC(CC[C@]5([H])[C@@]4([H])CC2)=O


Technical Data

Appearance:
White to off-white solid powder.

Purity:
>98% (or refer to the Certificate of Analysis)

Certificate of Analysis:

Safety Data Sheet (MSDS):

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Kanno Y, Ota R, Someya K, Kusakabe T, Kato K, Inouye Y. Selective androgen
receptor modulator, YK11, regulates myogenic differentiation of C2C12 myoblasts
by follistatin expression. Biol Pharm Bull. 2013;36(9):1460-5. PubMed PMID:
23995658.

2: Kanno Y, Hikosaka R, Zhang SY, Inoue Y, Nakahama T, Kato K, Yamaguchi A,
Tominaga N, Kohra S, Arizono K, Inouye Y.
(17α,20E)-17,20-[(1-methoxyethylidene)bis(oxy)]-3-oxo-19-norpregna-4,20-diene-21-
carboxylic acid methyl ester (YK11) is a partial agonist of the androgen
receptor. Biol Pharm Bull. 2011;34(3):318-23. PubMed PMID: 21372378.