ABT-080

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 527204

CAS#: 189498-56-4; 189498-57-5

Description: ABT-080, also known as VML-530, is a leukotriene synthesis inhibitor potentially for treatment of asthma.


Price and Availability

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Price

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ABT-080 is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 527204
Name: ABT-080
CAS#: 189498-56-4; 189498-57-5
Chemical Formula: C37H31N2NaO4
Exact Mass:
Molecular Weight: 590.6548
Elemental Analysis: C, 75.24; H, 5.29; N, 4.74; Na, 3.89; O, 10.83


Synonym: ABT-080; ABT080; ABT 080; VML-530; VML530; VML 530

IUPAC/Chemical Name: sodium 4,4-bis(4-(quinolin-2-ylmethoxy)phenyl)pentanoate

InChi Key: IQIPMOPRODKMFM-UHFFFAOYSA-M

InChi Code: InChI=1S/C37H32N2O4.Na/c1-37(23-22-36(40)41,28-12-18-32(19-13-28)42-24-30-16-10-26-6-2-4-8-34(26)38-30)29-14-20-33(21-15-29)43-25-31-17-11-27-7-3-5-9-35(27)39-31;/h2-21H,22-25H2,1H3,(H,40,41);/q;+1/p-1

SMILES Code: O=C([O-])CCC(C1=CC=C(OCC2=NC3=CC=CC=C3C=C2)C=C1)(C)C4=CC=C(OCC5=NC6=CC=CC=C6C=C5)C=C4.[Na+]


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


Additional Information

Related CAS#:

189498-56-4 (ABT-080)
189498-57-5 (ABT-080)


References

1: Kolasa T, Gunn DE, Bhatia P, Basha A, Craig RA, Stewart AO, Bouska JB, Harris RR, Hulkower KI, Malo PE, Bell RL, Carter GW, Brooks CD. Symmetrical bis(heteroarylmethoxyphenyl)alkylcarboxylic acids as inhibitors of leukotriene biosynthesis. J Med Chem. 2000 Aug 24;43(17):3322-34. PubMed PMID: 10966751.