EA-230

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 530004

CAS#: 503844-09-5

Description: EA-230 is a immunoregulator potentially for the treatment of renal failure.


Price and Availability

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Price

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EA-230 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 530004
Name: EA-230
CAS#: 503844-09-5
Chemical Formula: C15H27N5O6
Exact Mass: 373.2
Molecular Weight: 373.41
Elemental Analysis: C, 48.25; H, 7.29; N, 18.76; O, 25.71


Synonym: EA-230; NMPF-46; EA230; NMPF46; EA 230; NMPF 46; L-alanyl-L-glutaminylglycyl-L-valine

IUPAC/Chemical Name: (2S)-2-[[2-[[(2S)-5-amino-2-[[(2S)-2-aminopropanoyl]amino]-5-oxopentanoyl]amino]acetyl]amino]-3-methylbutanoic acid

InChi Key: DXRXYJYFADHAPA-AUTRQRHGSA-N

InChi Code: InChI=1S/C15H27N5O6/c1-7(2)12(15(25)26)20-11(22)6-18-14(24)9(4-5-10(17)21)19-13(23)8(3)16/h7-9,12H,4-6,16H2,1-3H3,(H2,17,21)(H,18,24)(H,19,23)(H,20,22)(H,25,26)/t8-,9-,12-/m0/s1

SMILES Code: CC(C)[C@H](NC(CNC([C@@H](NC([C@@H](N)C)=O)CCC(N)=O)=O)=O)C(O)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Gueler F, Shushakova N, Mengel M, Hueper K, Chen R, Liu X, Park JK, Haller H, Wensvoort G, Rong S. A novel therapy to attenuate acute kidney injury and ischemic allograft damage after allogenic kidney transplantation in mice. PLoS One. 2015 Jan 24;10(1):e0115709. doi: 10.1371/journal.pone.0115709. PubMed PMID: 25617900; PubMed Central PMCID: PMC4305280.