REC-2615 HCl
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 530142

CAS#: 173059-17-1

Description: REC-2615 HCl is a α1B-adrenoceptor antagonist potentially for the treatment of female sexual dysfunction.


Chemical Structure

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REC-2615 HCl
CAS# 173059-17-1

Theoretical Analysis

MedKoo Cat#: 530142
Name: REC-2615 HCl
CAS#: 173059-17-1
Chemical Formula: C26H34ClN5O5
Exact Mass: 0.00
Molecular Weight: 532.040
Elemental Analysis: C, 58.70; H, 6.44; Cl, 6.66; N, 13.16; O, 15.04

Price and Availability

Size Price Availability Quantity
10mg USD 295
50mg USD 895
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Synonym: REC-2615; Rec-15; 2615; REC2615; Rec15; REC 2615; Rec 15

IUPAC/Chemical Name: 1-(4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)-2-(2-isopropyl-6-methoxyphenoxy)ethan-1-one hydrochloride

InChi Key: YLPWNPUPMQZIKN-UHFFFAOYSA-N

InChi Code: InChI=1S/C26H33N5O5.ClH/c1-16(2)17-7-6-8-20(33-3)24(17)36-15-23(32)30-9-11-31(12-10-30)26-28-19-14-22(35-5)21(34-4)13-18(19)25(27)29-26;/h6-8,13-14,16H,9-12,15H2,1-5H3,(H2,27,28,29);1H

SMILES Code: O=C(N1CCN(C2=NC(N)=C3C=C(OC)C(OC)=CC3=N2)CC1)COC4=C(OC)C=CC=C4C(C)C.[H]Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info: Related CAS# 173059-17-1(REC-2615 hydrochloride) 173059-47-7(REC-2615 Free base)

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 532.04 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: da Silva ES, Flores RA, Cella EC, Levone BR, Taschetto AP, Kochenborger L, Terenzi MG, Faria MS, Paschoalini MA. Blockade of median raphe nucleus α1-adrenoceptor subtypes increases food intake in rats. Pharmacol Biochem Behav. 2014 Sep;124:350-5. doi: 10.1016/j.pbb.2014.06.010. PubMed PMID: 24955865.

2: Sironi G, Colombo D, Poggesi E, Leonardi A, Testa R, Rampin O, Bernabé J, Giuliano F. Effects of intracavernous administration of selective antagonists of alpha(1)-adrenoceptor subtypes on erection in anesthetized rats and dogs. J Pharmacol Exp Ther. 2000 Mar;292(3):974-81. PubMed PMID: 10688612.

3: Kim NN, Min K, Huang YH, Goldstein I, Traish AM. Biochemical and functional characterization of alpha-adrenergic receptors in the rabbit vagina. Life Sci. 2002 Nov 1;71(24):2909-20. PubMed PMID: 12377271.

4: Bayés M, Rabasseda X, Prous JR. Gateways to clinical trials. Methods Find Exp Clin Pharmacol. 2007 Nov;29(9):625-55. PubMed PMID: 18193114.