RAF709
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 406990

CAS#: 1628838-42-5

Description: RAF709 is a Raf kinase inhibitor.


Price and Availability

Size
Price

10mg
Not available
100mg
USD 750
1g
USD 3450
Size
Price

20mg
Not available
200mg
USD 1250
2g
USD 5450
Size
Price

50mg
USD 450
500mg
USD 2150
5g
USD 9650

RAF709, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received. Delivery time: overnight (USA/Canada); 3-5 days (worldwide). Shipping fee: from $30.00 (USA); from $45.00 (Canada); from $70.00 (international).


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 406990
Name: RAF709
CAS#: 1628838-42-5
Chemical Formula: C28H29F3N4O4
Exact Mass: 542.2141
Molecular Weight: 542.5592
Elemental Analysis: C, 61.99; H, 5.39; F, 10.50; N, 10.33; O, 11.80


Synonym: RAF709; RAF-709; RAF 709.

IUPAC/Chemical Name: N-(2-methyl-5'-morpholino-6'-((tetrahydro-2H-pyran-4-yl)oxy)-[3,3'-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide

InChi Key: FYNMINFUAIDIFL-UHFFFAOYSA-N

InChi Code: InChI=1S/C28H29F3N4O4/c1-18-24(15-22(17-32-18)34-26(36)19-3-2-4-21(13-19)28(29,30)31)20-14-25(35-7-11-38-12-8-35)27(33-16-20)39-23-5-9-37-10-6-23/h2-4,13-17,23H,5-12H2,1H3,(H,34,36)

SMILES Code: O=C(NC1=CN=C(C)C(C2=CC(N3CCOCC3)=C(OC4CCOCC4)N=C2)=C1)C5=CC(C(F)(F)F)=CC=C5


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Maxson JE, Abel ML, Wang J, Deng X, Reckel S, Luty SB, Sun H, Gorenstein J,
Hughes SB, Bottomly D, Wilmot B, McWeeney SK, Radich J, Hantschel O, Middleton
RE, Gray NS, Druker BJ, Tyner JW. Identification and Characterization of Tyrosine
Kinase Nonreceptor 2 Mutations in Leukemia through Integration of Kinase
Inhibitor Screening and Genomic Analysis. Cancer Res. 2016 Jan 1;76(1):127-38.
doi: 10.1158/0008-5472.CAN-15-0817. PubMed PMID: 26677978; PubMed Central PMCID:
PMC4703549.