Y16
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 406988

CAS#: 429653-73-6

Description: Y16, also known as RhoA-IN-Y16, is a RhoA inhibitor, Y16 blocks the binding of LARG, a DBL-family Rho guanine nucleotide exchange factor, with Rho (Kd = 80 nM). Y16 specifically inhibits LARG catalyzed activation of RhoA and RhoA signaling pathways. Y16 blocks the growth and migration of MCF7 breast cancer cells.


Price and Availability

Size
Price

100mg
USD 850
1g
USD 2950
Size
Price

200mg
USD 1450
2g
USD 3850
Size
Price

500mg
USD 2150
5g
USD 5950

Y16, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received. Delivery time: overnight (USA/Canada); 3-5 days (worldwide). Shipping fee: from $30.00 (USA); from $45.00 (Canada); from $70.00 (international).


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 406988
Name: Y16
CAS#: 429653-73-6
Chemical Formula: C24H20N2O3
Exact Mass: 384.1474
Molecular Weight: 384.435
Elemental Analysis: C, 74.98; H, 5.24; N, 7.29; O, 12.49


Synonym: RhoA-IN-Y16; Y16; Y-16; Y 16.

IUPAC/Chemical Name: (E)-4-(3-((3-methylbenzyl)oxy)benzylidene)-1-phenylpyrazolidine-3,5-dione

InChi Key: ITMLWGWTDWJSRZ-PXLXIMEGSA-N

InChi Code: InChI=1S/C24H20N2O3/c1-17-7-5-9-19(13-17)16-29-21-12-6-8-18(14-21)15-22-23(27)25-26(24(22)28)20-10-3-2-4-11-20/h2-15H,16H2,1H3,(H,25,27)/b22-15+

SMILES Code: O=C(/C1=C\C2=CC=CC(OCC3=CC=CC(C)=C3)=C2)NN(C4=CC=CC=C4)C1=O


Technical Data

Appearance:
White to off-white solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490