A-123189

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 531343

CAS#: 255713-53-2

Description: A-123189 is a novel, selective and potent alpha1D antagonist.


Price and Availability

Size
Price

Size
Price

Size
Price

A-123189 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

img

Theoretical Analysis

MedKoo Cat#: 531343
Name: A-123189
CAS#: 255713-53-2
Chemical Formula: C26H28N4O3S
Exact Mass: 476.1882
Molecular Weight: 476.595
Elemental Analysis: C, 65.52; H, 5.92; N, 11.76; O, 10.07; S, 6.73


Synonym: A-123189

IUPAC/Chemical Name: 3-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-5-(3-methylphenyl)-1H-thieno[3,2-e]pyrimidine-2,4-dione

InChi Key: PANBMHHKBRMYAL-UHFFFAOYSA-N

InChi Code: InChI=1S/C26H28N4O3S/c1-18-6-5-7-19(16-18)20-17-34-24-23(20)25(31)30(26(32)27-24)15-12-28-10-13-29(14-11-28)21-8-3-4-9-22(21)33-2/h3-9,16-17H,10-15H2,1-2H3,(H,27,32)

SMILES Code: O=C1N(CCN2CCN(C3=CC=CC=C3OC)CC2)C(C(C(C4=CC=CC(C)=C4)=CS5)=C5N1)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Carroll WA, Sippy KB, Esbenshade TA, Buckner SA, Hancock AA, Meyer MD. Two novel and potent 3-[(o-methoxyphenyl)piperazinylethyl]-5-phenylthien. Bioorg Med Chem Lett. 2001 May 7;11(9):1119-21. PubMed PMID: 11354357.