Benactyzine Hydrochloride
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 329310

CAS#: 57-37-4 (HCl)

Description: Benactyzine Hydrochloride, also known as Suavitil, is a centrally acting muscarinic antagonist. Benactyzine has been used in the treatment of depression and is used in research to investigate the role of cholinergic systems on behavior.


Price and Availability

Size
Price

10g
USD 170
Size
Price

Size
Price

Benactyzine Hydrochloride (Suavitil) purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 329310
Name: Benactyzine Hydrochloride
CAS#: 57-37-4 (HCl)
Chemical Formula: C20H26ClNO3
Exact Mass:
Molecular Weight: 363.882
Elemental Analysis: C, 66.02; H, 7.20; Cl, 9.74; N, 3.85; O, 13.19


Synonym: Benactyzine Hydrochloride; EA 2092; EA-2092; EA2092; Suavitil; Phebex; Phobex; Cedad; Cevanol; Deprol; Lucidil; Morcain; Nutinal; Parasan

IUPAC/Chemical Name: 2-(diethylamino)ethyl 2-hydroxy-2,2-diphenylacetate hydrochloride

InChi Key: ZCEHOOLYWQBGQO-UHFFFAOYSA-N

InChi Code: InChI=1S/C20H25NO3.ClH/c1-3-21(4-2)15-16-24-19(22)20(23,17-11-7-5-8-12-17)18-13-9-6-10-14-18;/h5-14,23H,3-4,15-16H2,1-2H3;1H

SMILES Code: OC(C1=CC=CC=C1)(C2=CC=CC=C2)C(OCCN(CC)CC)=O.[H]Cl


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


Additional Information

Related CAS#

302-40-9 (Benactyzine)
57-37-4 (Benactyzine Hydrochloride)


References

1: Brown B, Haegerstrom-Portnoy G, Baker R, Adams AJ, Jones RT. Effects of benactyzine hydrochloride on dynamic vision functions. Aviat Space Environ Med. 1982 Nov;53(11):1123-8. PubMed PMID: 7150174.

2: Siedlanowska H, Krówczyński L. [Kinetics of decomposition of benzilic acid esters. 3. Study of kinetics of decomposition of benactyzine hydrochloride and methyliodide and diphemin hydrochloride]. Acta Pol Pharm. 1966;23(6):505-16. Polish. PubMed PMID: 5960081.

3: GLOW PH. The blocking effect of benactyzine hydrochloride on a behaviour disturbance induced with lysergic acid diethylamide. Br J Psychol. 1959 Nov;50:338-48. PubMed PMID: 13828510.

4: BATEMAN JC, CARLTON HM. Meprobamate and benactyzine hydrochloride (deprol) as adjunctive therapy for patients with advanced cancer. Antibiotic Med Clin Ther (New York). 1959 Nov;6:648-52. PubMed PMID: 13797484.

5: LAMPHIER TA. Benactyzine hydrochloride; the treatment of one hundred hospitalized patients. Conn Med. 1959 Apr;23(4):220-3. PubMed PMID: 13639572.

6: SMITH GW, UHR L, POLLARD JC, MILLER JG. An exploratory study of the behavioral effects of suavitil (benactyzine hydrochloride). Med Bull (Ann Arbor). 1958 Oct;24(10):402-7. PubMed PMID: 13603890.

7: ALEXANDER L. Chemotherapy of depression; use of meprobamate combined with benactyzine (2-diethylaminoethyl benzilate) hydrochloride. J Am Med Assoc. 1958 Mar 1;166(9):1019-23. PubMed PMID: 13502099.

8: WELSH AL, EDE M. Experience with benactyzine hydrochloride (suavitil) in dermatologic practice. AMA Arch Derm. 1957 Oct;76(4):466-70. PubMed PMID: 13457433.

9: MACLEAN RE. Benactyzine hydrochloride (suavitil) in out-patient psychiatric treatment: preliminary study. Med J Aust. 1957 Jan 19;44(3):67-70. PubMed PMID: 13399522.

10: Longrée R. [The hydroxylaminolysis kinetics of benactyzine hydrochloride (author's transl)]. J Pharm Belg. 1977 Mar-Apr;32(2):167-78. French. PubMed PMID: 894477.

11: SETTEL E. Treatment of depression in the elderly with a meprobamate-benactyzine hydrochloride combination (deprol). Antibiotic Med Clin Ther (New York). 1960 Jan;7:28-32. PubMed PMID: 14445207.

12: RUCHWARGER A. Use of deprol (meprobamate combined with benactyzine hydrochloride) in the office treatment of depression. Med Ann Dist Columbia. 1959 Aug;28(8):438-41. PubMed PMID: 13673692.

13: ALEXANDER L. Meprobamate combined with 2-diethyl-aminoethyl benzilate hydrochloride (benactyzine). Dis Nerv Syst. 1958 Jul;19(7, Part 2):52-3. PubMed PMID: 13561919.

14: AYD FJ Jr. A clinical report on benactyzine hydrochloride. N Engl J Med. 1957 Oct 3;257(14):669-70. PubMed PMID: 13477367.

15: BERGER FM, HENDLEY CD, LYNES TE. Pharmacology of the psychotherapeutic drug benactyzine (beta-diethylaminoethyl benzilate hydrochloride). Proc Soc Exp Biol Med. 1956 Jul;92(3):563-6. PubMed PMID: 13359467.