Batifiban

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 326971

CAS#: 710312-77-9

Description: Batifiban is a glycoprotein IIb/IIIa antagonist potentially for the treatment of coronary artery disease.


Price and Availability

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Batifiban is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 326971
Name: Batifiban
CAS#: 710312-77-9
Chemical Formula: C34H47N11O9S2
Exact Mass: 817.3
Molecular Weight: 817.938
Elemental Analysis: C, 49.93; H, 5.79; N, 18.84; O, 17.60; S, 7.84


Synonym: Batifiban

IUPAC/Chemical Name: 2-((3R,11S,17S,20S,25aS)-20-((1H-indol-3-yl)methyl)-3-carbamoyl-11-(3-guanidinopropyl)-1,9,12,15,18,21-hexaoxodocosahydro-7H-pyrrolo[2,1-g][1,2]dithia[5,8,11,14,17,20]hexaazacyclotricosin-17-yl)acetic acid

InChi Key: UUQHAAWMCLITRZ-KEOOTSPTSA-N

InChi Code: InChI=1S/C34H47N11O9S2/c35-29(50)24-17-56-55-12-9-26(46)41-21(7-3-10-38-34(36)37)30(51)40-16-27(47)42-22(14-28(48)49)31(52)43-23(13-18-15-39-20-6-2-1-5-19(18)20)33(54)45-11-4-8-25(45)32(53)44-24/h1-2,5-6,15,21-25,39H,3-4,7-14,16-17H2,(H2,35,50)(H,40,51)(H,41,46)(H,42,47)(H,43,52)(H,44,53)(H,48,49)(H4,36,37,38)/t21-,22-,23-,24-,25-/m0/s1

SMILES Code: O=C([C@H](CC(O)=O)NC(CNC([C@@H](NC(CCSSC[C@H](NC1=O)C(N)=O)=O)CCCNC(N)=N)=O)=O)N[C@H](C(N2[C@H]1CCC2)=O)CC3=CNC4=C3C=CC=C4


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: He XM, Zhou Y, Li J, Wu SL, Jia MM, Liu MZ, Chen H, Chen K, Li SF, Wang YH, Li
WY. Pharmacokinetic and pharmacodynamic properties of batifiban coadministered
with antithrombin agents in Chinese healthy volunteers. J Huazhong Univ Sci
Technolog Med Sci. 2013 Oct;33(5):786-90. doi: 10.1007/s11596-013-1198-4. PubMed
PMID: 24142738.

2: Chen H, Qiao J, Li Q, Deng J, Tan Z, Guo T, Li W. Safety, pharmacokinetic and
pharmacodynamic studies of batifiban injection following single- and
multiple-dose administration to healthy Chinese subjects. J Huazhong Univ Sci
Technolog Med Sci. 2009 Feb;29(1):12-8. doi: 10.1007/s11596-009-0103-7. Epub 2009
Feb 18. PubMed PMID: 19224155.