Padsevonil

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 327019

CAS#: 1294000-61-5

Description: Padsevonil (also known as UCB-0942) is an antiepileptic, with the intended use being for patients with highly drug-resistent epilepsy.


Price and Availability

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Padsevonil (UCB-0942) is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 327019
Name: Padsevonil
CAS#: 1294000-61-5
Chemical Formula: C14H14ClF5N4O2S
Exact Mass: 432.0446
Molecular Weight: 432.794
Elemental Analysis: C, 38.85; H, 3.26; Cl, 8.19; F, 21.95; N, 12.95; O, 7.39; S, 7.41


Synonym: Padsevonil; UCB-0942; UCB 0942; UCB0942

IUPAC/Chemical Name: (R)-4-(2-chloro-2,2-difluoroethyl)-1-((2-(methoxymethyl)-6-(trifluoromethyl)imidazo[2,1-b][1,3,4]thiadiazol-5-yl)methyl)pyrrolidin-2-one

InChi Key: DCXFIOLWWRXEQH-SSDOTTSWSA-N

InChi Code: InChI=1S/C14H14ClF5N4O2S/c1-26-6-9-22-24-8(11(14(18,19)20)21-12(24)27-9)5-23-4-7(2-10(23)25)3-13(15,16)17/h7H,2-6H2,1H3/t7-/m1/s1

SMILES Code: O=C1N(CC2=C(C(F)(F)F)N=C3SC(COC)=NN32)C[C@@H](CC(F)(Cl)F)C1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Zaccara G, Schmidt D. Do traditional anti-seizure drugs have a future? A review of potential anti-seizure drugs in clinical development. Pharmacol Res. 2016 Feb;104:38-48. doi: 10.1016/j.phrs.2015.12.011. Epub 2015 Dec 12. Review. PubMed PMID: 26689774.