Meluadrine tartrate

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 326862

CAS#: 134865-37-5 (tartrate)

Description: Meluadrine, also known as (R)-Tulobuterol; Tulobuterol-(R); HSR-81 (R); HSR-81, is an β2 adrenergic receptor agonist potentially use to prevent preterm labor.

Chemical Structure

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Meluadrine tartrate
CAS# 134865-37-5 (tartrate)
Instruction

Theoretical Analysis

MedKoo Cat#: 326862
Name: Meluadrine tartrate
CAS#: 134865-37-5 (tartrate)
Chemical Formula: C16H24ClNO8
Exact Mass: 0.00
Molecular Weight: 393.817
Elemental Analysis: C, 48.80; H, 6.14; Cl, 9.00; N, 3.56; O, 32.50

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Related CAS #: 134865-37-5 (tartrate)   134865-33-1 (free base)    

Synonym: (R)-Tulobuterol; Tulobuterol-(R); HSR-81 (R); HSR-81; Meluadrine tartrate

IUPAC/Chemical Name: (R)-4-(2-(tert-butylamino)-1-hydroxyethyl)-3-chlorophenol (2R,3R)-2,3-dihydroxysuccinate

InChi Key: VVIVBRYHTLRZGY-MBANBULQSA-N

InChi Code: InChI=1S/C12H18ClNO2.C4H6O6/c1-12(2,3)14-7-11(16)9-5-4-8(15)6-10(9)13;5-1(3(7)8)2(6)4(9)10/h4-6,11,14-16H,7H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/t11-;1-,2-/m01/s1

SMILES Code: O[C@@H](CNC(C)(C)C)C1=CC=C(O)C=C1Cl.O=C(O)[C@H](O)[C@@H](O)C(O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info: Related CAS# CAS No. 134865-33-1(Meluadrine) CAS#134865-37-5(Meluadrine tartrate)

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 393.82 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Matsuda Y, Kouno S, Sakamoto H, Ikenoue T. Effects of meluadrine tartrate on
maternal metabolic responses and fetal hemodynamics in pregnant goats. Jpn J
Pharmacol. 2002 Oct;90(2):114-20. PubMed PMID: 12419880.


2: Matsuda Y, Kouno S, Sakamoto H, Ikenoue T. Effects of meluadrine tartrate and
ritodrine hydrochloride on oxytocin-induced uterine contraction, uterine arterial
blood flow and maternal cardiovascular function in pregnant goats. Jpn J
Pharmacol. 2002 Oct;90(2):107-13. PubMed PMID: 12419879.


3: Matsuo K, Yamamoto Y, Kado N, Yamazaki M, Nagata O, Kato H, Tsuji A.
Racemization kinetics of meluadrine tartrate in aqueous solution. Chem Pharm Bull
(Tokyo). 2001 Jan;49(1):101-4. Erratum in: Chem Pharm Bull (Tokyo) 2001
Jun;49(6):794. PubMed PMID: 11201211.