PF-04995274
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 525952

CAS#: 1331782-27-4

Description: PF-04995274 is a 5-HT4 receptor partial agonist. It thought to act centrally as a pro-cognitive agent that being developed for the treatment of Alzheimer's disease (AD).


Price and Availability

Size
Price

10mg
USD 150
100mg
USD 650
1g
USD 3150
Size
Price

25mg
USD 250
200mg
USD 1050
2g
USD 4950
Size
Price

50mg
USD 450
500mg
USD 1950
5g
Ask price

PF-04995274, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received. Delivery time: overnight (USA/Canada); 3-5 days (worldwide). Shipping fee: from $30.00 (USA); from $45.00 (Canada); from $70.00 (international).


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 525952
Name: PF-04995274
CAS#: 1331782-27-4
Chemical Formula: C23H32N2O6
Exact Mass: 432.226
Molecular Weight: 432.52
Elemental Analysis: C, 63.87; H, 7.46; N, 6.48; O, 22.19


Synonym: PF-04995274; PF 04995274; PF04995274; PF-4995274; PF 4995274; PF4995274.

IUPAC/Chemical Name: (R)-4-((4-(((4-(Tetrahydrofuran-3-yloxy)-1,2-benzisoxazol-3-yl)oxy)methyl)piperidin-1-yl)methyl)tetrahydro-2H-pyran-4-ol

SMILES Code: OC1(CN2CCC(COC3=NOC4=C3C(O[C@H]5COCC5)=CC=C4)CC2)CCOCC1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Nirogi R, Kandikere V, Bhyrapuneni G, Saralaya R, Ajjala DR, Aleti RR, Rasheed MA. In-vivo rat striatal 5-HT4 receptor occupancy using non-radiolabelled SB207145. J Pharm Pharmacol. 2013 May;65(5):704-12. doi: 10.1111/jphp.12030. Epub 2013 Jan 25. PubMed PMID: 23600388.