Ono EI-601

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 525789

CAS#: 155023-59-9

Description: Ono EI-601 is the main metabolite of the human neutrophil elastase inhibitor ONO-5046. In plasma and urine by direct injection column-switching HPLC proved to be useful for pharmacokinetic, toxicological and clinical studies.

Chemical Structure

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Ono EI-601
CAS# 155023-59-9
Instruction

Theoretical Analysis

MedKoo Cat#: 525789
Name: Ono EI-601
CAS#: 155023-59-9
Chemical Formula: C15H14N2O6S
Exact Mass: 350.06
Molecular Weight: 350.347
Elemental Analysis: C, 51.42; H, 4.03; N, 8.00; O, 27.40; S, 9.15

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Ono-EI-601; OnoEI601; Ono EI 601; Ono-EI 601; Ono EI-601

IUPAC/Chemical Name: 2-(2-(4-hydroxyphenylsulfonamido)benzamido)acetic acid

InChi Key: QBMYNMQQDCMRPR-UHFFFAOYSA-N

InChi Code: InChI=1S/C15H14N2O6S/c18-10-5-7-11(8-6-10)24(22,23)17-13-4-2-1-3-12(13)15(21)16-9-14(19)20/h1-8,17-18H,9H2,(H,16,21)(H,19,20)

SMILES Code: O=C(O)CNC(C1=CC=CC=C1NS(=O)(C2=CC=C(O)C=C2)=O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 350.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Shintani T, Takamoto M, Sawada M, Aishita H, Nakagawa T. Simultaneous determination of human neutrophil elastase inhibitor (ONO-5046) and its metabolite in plasma and urine by direct injection column-switching HPLC. J Pharm Biomed Anal. 1994 Mar;12(3):397-405. PubMed PMID: 8031941.