Garenoxacin mesylate [USAN]
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 525152

CAS#: 223652-90-2

Description: Garenoxacin mesylate [USAN] is a novel oral des-fluoro quinolone with potent antimicrobial activity against common respiratory pathogens, including resistant strains and Gram-positive and Gram-negative bacterial infections.


Price and Availability

Size
Price

10mg
USD 230
Size
Price

50mg
USD 570
Size
Price

Garenoxacin mesylate, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 525152
Name: Garenoxacin mesylate [USAN]
CAS#: 223652-90-2
Chemical Formula: C24H26F2N2O8S
Exact Mass:
Molecular Weight: 540.53
Elemental Analysis: C, 53.33; H, 4.85; F, 7.03; N, 5.18; O, 23.68; S, 5.93


Synonym: Garenoxacin mesylate [USAN]; BMS-284756-01; Garenoxacin mesylate; Garenoxacin mesylate hydrate; T-3811ME.

IUPAC/Chemical Name: 1-Cyclopropyl-8-(difluoromethoxy)-7-((1R)-1-methyl-2,3-dihydro-1H-isoindol-5-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid monomethanesulfonate monohydrate

InChi Key: IGTHEWGRXUAFKF-NVJADKKVSA-N

InChi Code: InChI=1S/C23H20F2N2O4.CH4O3S.H2O/c1-11-15-5-2-12(8-13(15)9-26-11)16-6-7-17-19(21(16)31-23(24)25)27(14-3-4-14)10-18(20(17)28)22(29)30;1-5(2,3)4;/h2,5-8,10-11,14,23,26H,3-4,9H2,1H3,(H,29,30);1H3,(H,2,3,4);1H2/t11-;;/m1../s1

SMILES Code: C[C@@H]1c2ccc(cc2CN1)c3ccc4c(c3OC(F)F)n(cc(c4=O)C(=O)O)C5CC5.CS(=O)(=O)O.O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Takagi H, Tanaka K, Tsuda H, Kobayashi H. Clinical studies of garenoxacin. Int J Antimicrob Agents. 2008 Dec;32(6):468-74. doi: 10.1016/j.ijantimicag.2008.06.032. Epub 2008 Sep 13. Review. PubMed PMID: 18790608.