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MedKoo product information: Norepinephrine
Norepinephrine is the US name for noradrenaline, a catecholamine with multiple roles including as a hormone and a neurotransmitter. Areas of the body that produce or are affected by norepinephrine are described as noradrenergic.
Norepinephrine is synthesized from tyrosine as a precursor, and packed into synaptic vesicles. It performs its action by being released into the synaptic cleft, where it acts on adrenergic receptors, followed by the signal termination, either by degradation of norepinephrine, or by uptake by surrounding cells.
Norepinephrine is currently being developed by ProCertus BioPharm for the following indication: (1) prevention of radiodermatitis patients undergoing radiation therapy; (2) prevention of oral mucositis patients undergoing radiation therapy; (3) prevention of chemo- and radio-therapy-induced alopecia.
Current developer: ProCertus BioPharm.
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