MedKoo product information:

HQK-1004 

HQK-1004 acts by inducing the expression of a gene for a viral protein that is the target of several common anti-viral drugs, including GCV, which eradicate virally infected cells. The gene that makes this target protein is present in EBV infected tumor cells, but it is not expressed, thus rendering these cells resistant to anti-viral therapeutics. To overcome this problem, HemaQuest has developed a proprietary therapeutic approach using HQK-1004, which enables the expression of the viral protein that is the target of anti-viral drugs. Combining HQK-1004 with anti-viral therapeutics now enables the killing of viral-infected tumor cells, while uninfected cells should not be affected.  

Current developer:    HemaQuest Pharmaceuticals.