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MedKoo product information:

Fludarabine

MedKoo Code#: 201380

Name: Fludarabine

CAS#: 146-78-1

 

Synonym:   fludara;2-Fluoro Ara-A;Fludarabinum;F-Ara-A;Fludarabina;2-F-ara-A;CCRIS 3382;HSDB 6964.

 

IUPAC/Chemical name: 

(2R,3R,4R,5S)-2-(6-amino-2-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

Chemical structure: Theoretical analysis

 

 

Chemical Formula: C10H12FN5O4

Exact Mass: 285.08733

Molecular Weight: 285.23178 m/z: 285.08733 (100.0%), 286.09069 (10.8%), 286.08437 (1.8%)

Elemental Analysis: C, 42.11; H, 4.24; F, 6.66; N, 24.55; O, 22.44

Availability and price:

This agent is not in stock, which may be available through custom synthesis. To inquire quotation and lead time or to ask questions, please send email to sales@medkoo.com to describe your needs. A representative will respond your email shortly. We offer big discount for orders of bulk quantities.

 

Quality control data:

Product will be shipped with supporting analytical data.

 

 

Information about this agent

Fludarabine is highly effective in the treatment of chronic lymphocytic leukemia, producing higher response rates than alkylating agents such as chlorambucil alone.Fludarabine is used in various combinations with cyclophosphamide, mitoxantrone, dexamethasone and rituximab in the treatment of indolent non-Hodgkins lymphomas. As part of the FLAG regimen, fludarabine is used together with cytarabine and granulocyte colony-stimulating factor in the treatment of acute myeloid leukaemia. Because of its immunosuppressive effects, fludarabine is also used in some conditioning regimens prior to non myeloablative allogeneic stem cell transplant.

 

Current developer:   Xanthus Pharmaceuticals Inc

 

References

 

 

 

Contact MedKoo:

Email: sales@medkoo.com

 

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